Prior COVID vaccination induces a more robust antibody response to Omicron

A recent study posted to the medRxiv* preprint server assessed the impact of prior severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccination on the human immune response against SARS-CoV-2 Omicron infection. Various studies have reported lower susceptibility of the SARS-CoV-2 Omicron (B.1.1.529) variant against neutralizing antibodies. Therefore, it is necessary to understand the potential of previous SARS-CoV-2 infections in modifying the human immune response against the novel Omicron variant.