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Women who are pregnant or nursing should receive a COVID booster vaccination


In the current work, the researchers examined humoral immunity elicited by the booster dose of SARS-CoV-2 mRNA vaccines in 63 subjects comprising breastfeeding, pregnant and age-matched nonpregnant females. They studied the antibody response to the spike (S) proteins of the SARS-CoV-2 Omicron and ancestral strains in a group of 12 nursing, 31 pregnant, and 20 nonpregnant age-matched volunteers who received an mRNA-1273 or BNT162b2 booster dose after completing the primary COVID-19 vaccination. Further, the researchers analyzed the transmission of vaccine-triggered antibodies in 15 maternal-cord pairs at delivery. The eligible subjects were lactating, pregnant, and nonpregnant women aged 18 to 45 years. Moreover, all included participants were vaccinated with SARS-CoV-2 mRNA booster dose between August and December 2021. The participants were selected from two tertiary care hospitals by practitioners or were self-referred. Blood samples were taken from all volunteers four weeks following the booster dose vaccination and at delivery in pregnant women. Furthermore, umbilical cord and maternal blood were obtained during delivery for 15 women who gave birth during the research period.

News-Medical.Net - May 23, 2022

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