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How can countries stretch COVID vaccine supplies? Scientists are divided over dosing strategies


Amid skyrocketing coronavirus infections, some countries are attempting to stretch limited supplies of COVID-19 vaccines by reducing doses or changing vaccination schedules from those shown to be effective in clinical trials. But data are scarce on the impact of such measures, and scientists are split over whether they are worth the risks. “It might be fine,” says virologist Dan Barouch at Harvard Medical School in Boston, Massachusetts. “But we should stick with what’s been proven to work, because we want it to work. We don’t want to be creative for some unclear benefit and then have an unexpected problem.”

Nature.com - January 12, 2021

View the full story here: https://www.nature.com/articles/d41586-021-00001-6