No anaphylaxis after second dose of mRNA COVID vaccine, study finds

People who had a severe allergic reaction to their first dose of mRNA COVID-19 vaccine had no issues after their second dose, according to a retrospective multicenter US study in JAMA Internal Medicine. Allergic reactions are estimated to occur in up to 2% of people after their first mRNA COVID-19 vaccine dose, with anaphylaxis reported in as many as 2.5 per 10,000 vaccinees. The authors said that the results demonstrate that a second dose of the Pfizer or Moderna COVID-19 vaccine is safe for those who had an allergic reaction to the first dose