Are pockets of Covid in the gut causing long-term symptoms?

Since the early days of the pandemic it has been clear some people shed genetic material from the virus in their stools for months after catching Covid-19. The findings were initially regarded as a curiosity, but there is mounting evidence to support the idea that persistent pockets of coronavirus – in the gut, or elsewhere – may be contributing to long Covid. Earlier this month, Prof David R Walt and colleagues at Harvard Medical School announced that they had detected Sars-CoV-2 proteins – most commonly the viral spike protein – in the blood of 65% of the long Covid patients they tested, up to 12 months after they were first diagnosed. Though small and preliminary, the study provides some of the most compelling evidence yet for the idea that reservoirs of the virus could be contributing to people’s long-term ill health. “The half-life of spike protein in the body is pretty short, so its presence indicates that there must be some kind of active viral reservoir,” Walt said.