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Coronavirus antibodies may not help with cure, after Dutch study sees harmful effect in ICU patients


Researchers led by a professor in the Netherlands report that they might have found an important clue that may answer why immunoglobulin G appears only when patients are ill enough to be admitted to ICU. AFPResearchers led by a professor in the Netherlands report that they might have found an important clue that may answer why immunoglobulin G appears only when patients are ill enough to be admitted to ICU. Researchers led by a professor in the Netherlands report that they might have found an important clue that may answer why immunoglobulin G appears only when patients are ill enough to be admitted to ICU. Antibodies generated by the immune system to neutralise the novel coronavirus could cause severe harm or even kill the patient, according to a study by Dutch scientists. Immunoglobulin G (IgG) is a fork-shaped molecule produced by adaptive immune cells to intercept foreign invaders. Each type of IgG targets a specific type of pathogen. The IgG for Sars-CoV-2, the virus causing Covid-19, fights off the virus by binding with the virus' unique spike protein to reduce its chance of infecting human cells. They usually appear a week or two after the onset of illness, when the symptoms of most critically-ill patients suddenly get worse. A research team led by Professor Menno de Winther from the University of Amsterdam in the Netherlands said they might have found an important clue that may answer why the IgG appears only when patients are ill enough to be admitted to the intensive care unit (ICU).

South China Morning Post - July 14, 2020

View the full story here: https://www.scmp.com/news/china/science/article/3093162/coronavirus-antibodies-may-not-help-cure-after-dutch-study-sees